Rochester, NY 7/14/2009 11:13:29 PM
DCGN - DCGN Find Out 2nd Common Variation Increased Risk for Atrial Fibrillation and Stroke
deCODE genetics, Inc.
deCODE genetics, Inc., DCGN
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Scientists at deCODE genetics and colleagues from Europe and the United States today report the discovery of a common single-letter variant in the sequence of the human genome conferring increased risk of atrial fibrillation and stroke. The findings will be integrated directly into the deCODE AF reference laboratory test for gauging individual risk of AF and stroke and helping to identify stroke patients who may benefit from enhanced monitoring for AF. The new SNP is in the ZFHX3 gene on chromosome 16q22, and the more than one third of people of European descent who carry one copy are at approximately 20% greater risk of AF and cardioembolic stroke than are individuals who carry none. AF is the most common type of cardiac arrhythmia, and is a major risk factor for stroke.
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