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Medefile International, Inc. (OTC:MDFI) surged 30% at $0.0032 on 12 million shares in the early morning trade on no news. Medefile International, Inc. (Medefile), through its subsidiary, Medefile, Inc., has developed a system for gathering, digitizing, storing and distributing information for the healthcare field. The Company has created a system for gathering and digitizing medical records so that individuals can have a record of all of their medical visits. Medefile's primary product is the MedeFile system, a secure system for gathering and maintaining medical records. The MedeFile system is designed to gather all of its members' medical records and create a single, comprehensive medical record that is accessible round the clock. As of December 31, 2008, MedeFile had approximately 2,600 members. The Company generates revenue from licensing the right to utilize its software for the storage and distribution of healthcare information to individuals and affinity groups.

Health Sciences Group, Inc. (OTC:HESG)  is trading up 100% at $0.0002 on 4.5 million shares. Health Sciences Group, Inc. identifies, develops and commercializes products and functional food ingredients derived from natural sources to provide consumers and healthcare professionals with preventive healthcare alternatives. The Company has two operating subsidiaries: BioSelect Innovations, Inc. and Swiss Research, Inc. BioSelect Innovations has developed a number of product formulations. These patents address the integration of selective traditional over-the-counter generic drugs with complementary alternative medications, such as vitamins, herbs and other natural nutraceutical supplements. Swiss Research is a diet and nutrition products company, which markets and sells Shugr, a zero-calorie and diabetic safe sugar substitute with the look, taste and baking qualities of cane sugar. The Company will launch its new product, Sequesterol Advance Cardio Formula in April 2006.

 HARD TO TREAT DISEAS (PINK: HTDS) is one of the top traded and percentage gainer. In an early session, it surged 48% on over 594 million shares on no news.

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