Scottsdale 11/28/2012 11:00:00 PM
News / Health Care

Prana Biotechnology (PRAN) Completes Patient Enrollment in Alzheimer Trial

QualityStocks would like to highlight Prana Biotechnology (NASDAQ: PRAN). The company has developed a proprietary library of class-leading chemical compounds. This library is combined with a drug development program to explore novel therapeutics in multiple disease indications. The scientific focus of the company is upon neurological diseases, particularly Alzheimer‘s, Parkinson‘s and Huntington‘s diseases. The company’s research centers on the interactions between certain metals in the human body and proteins.

In the company’s news yesterday,

Prana Biotechnology announced that it has completed enrollment in the IMAGINE trial, a 12-month Phase II trial testing PBT2, the company’s drug in development for Alzheimer’s disease. This disease affects more than 26 million people around the globe. All currently available treatments only offer some degree of symptomatic relief, but none change the course of the disease. PBT2 has the potential to actually treat the disease.

The Phase II study is a double-blind placebo controlled trial and has enrolled 41 patients with mild Alzheimer’s disease in Melbourne, Australia. Trial participants are undergoing brain scans to measure PBT2′s effect on amyloid deposits in the brain and effects on increasing brain activity. Neuropsychological Test Battery (NTB) is being used to measure the cognition effects.

Scientific data supporting the belief that PBT2 can bring clinical benefit to patients is extensive. An earlier 12-week Alzheimer’s disease trial showed the drug significantly reduced the level of Abeta protein in the spinal fluid of treated patients as well as improving their cognitive function. PBT2 is believed to restore neuronal health by binding and redistributing brains metals (copper, zinc) that have become imbalanced.

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