The Fantastic Mr. Fox actor - who has no children - claims he owes his Oceans 11 co-star a favour and is willing help out with his six children.
He joked to BANG Showbiz: I am planning to adopt. I am going to adopt some of Brad Pitt’s kids. I owe him.
George previously revealed he has no plans to become a father, but spends time with Brad, his partner Angelina Jolie and their large brood whenever he feels lonely.
He said: Even one kid running around my villa makes me nervous, so I'm definitely not a candidate for father of the year. If I need to surround myself with children and feel like I have this big extended family, I can always call Brad and Angelina and ask them to stay with me, just to remind myself why I'm so happy."
George has also revealed he formed such a close bond with his Fantastic Mr. Fox co-star Jason Schwartzman he feels like a parent to him.
When asked if voicing the animated family movie had made him broody, George said: Broody? That’s a word that Americans don’t understand. Just having Jason here next me was like having a son. And he just got married by the way, so it will soon be like being a grandfather!
The 48-year-old actor is currently dating Italian TV presenter Elisabetta Canalis.