The Monsters vs. Aliens actress - who was born in Louisiana, raised in Tennessee and now lives in Los Angeles - always thought she would settle down in her hometown and live near her parents John and Betty and her older brother John.
She said: Sometimes it’s really difficult for me, being far away from home and living in Los Angeles. I never imagined that my children wouldn’t grow up next door to my brother’s children - or my mom and dad wouldn’t constantly be around.
Reese - who has 10-year-old Ava and Deacon, five, with her ex-husband Ryan Phillippe - also revealed her homesickness has led her to establish a big group of friends who had a similar upbringing to her.
The 33-year-old blonde star explained: At least I have a lot of southern friends in Los Angeles - I gravitate toward them.
Reese is currently dating her Rendition co-star Jake Gyllenhaal.
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