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AEterna Zentaris (Nasdaq: AEZS) $0.99. Today announced positive efficacy data from a Phase 2 study with its targeted cytotoxic peptide conjugate, AEZS-108 (formerly AN-152), in patients with advanced or recurrent endometrial cancer. In a personalized health care approach, the study selected patients with tumors expressing luteinizing hormone-releasing hormone (LHRH) receptors, the key element in the targeting mechanism of AEZS-108. Under the coordination of Prof. Gunter Emons, MD, Chairman of the Department of Obstetrics & Gynaecology at the University of Gottingen, Germany, this open-label, multi-center and multi-national Phase 2 study AGO-GYN 5, is being conducted by the German AGO Study Group in cooperation with clinical sites in Europe.
A preliminary evaluation has shown that the study AGO-GYN 5 met its predefined primary efficacy endpoint of 5 or more responder patients with endometrial cancer. The study is currently ongoing, and responders, as well as patients with stable disease after completion of treatment with AEZS-108, will be followed to assess the duration of progression-free survival and, ultimately, overall survival. Detailed analyses of the study results will be presented at forthcoming scientific conferences.
What They Do: AEterna Zentaris Inc. is a global biopharmaceutical company focused on endocrine therapy and oncology, with proven expertise in drug discovery, development and commercialization.
Cracker Barrel Old Country Store (Nasdaq: CRBL) $25.27. Today announced net income per diluted share of $0.78 for the first quarter of fiscal 2010, compared with $0.57 per diluted share in the first quarter of fiscal 2009, an increase of 36.8%. Net income for the first quarter of fiscal 2010 was $18.0 million compared with $12.8 million in the first quarter of fiscal 2009, which reflects a 16.7% increase in operating income and lower interest expense.
What They Do: Cracker Barrel Old Country Store® restaurants provide a friendly home-away-from-home in its old country stores and restaurants.
Fred's, Inc. (Nasdaq: FRED) $10.59. Today announced financial results for the third quarter and nine months ended October 31, 2009. For the third quarter of 2009, Fred's net income was $5.0 million or $0.13 per diluted share, down 17% from $6.1 million or $0.15 per diluted share in the same quarter last year, reflecting a significant increase in promotional programs and associated expenses. For the nine months ended October 31, 2009, net income increased 24% to $17.8 million or $0.45 per diluted share from net income of $14.4 million or $0.36 per diluted share for the first nine months of 2008.
Fred's total sales for the third quarter of fiscal 2009 increased 1% to $422.4 million from $418.0 million for the same period last year. Comparable store sales for the quarter increased 1.0% compared with a 1.4% increase in the third quarter last year. For the first nine months of 2009, total sales declined 1% to $1.315 billion from $1.329 billion in the year-earlier period. Excluding stores closed last year, total sales from ongoing stores increased 1% in the first nine months of 2009 versus the year-earlier period. Comparable store sales for the 2009 year-to-date period increased 0.8% versus 2.9% in the prior-year period.
What They Do: Fred's, Inc. operates 665 discount general merchandise stores, including 24 franchised Fred's stores at year-end.
Jacada Ltd. (Nasdaq: JCDA) $1.37. Today announced that it has entered into an agreement with a new customer, the Swedish subsidiary of the world’s largest gas and power company, E.ON. The agreement with E.ON is the first Jacada utility contract in Europe and signals expansion into the Nordics region.
E.ON Nordic is part of the E.ON Group, one of the world's largest investor-owned power and gas companies, with roughly 93,500 employees and EUR87 billion in sales in 2008. The utility provider is working with Jacada to streamline and automate key call center processes, such as “move in” and “move out,” in order to provide a better customer experience.
What They Do: Jacada provides solutions that optimize and improve the effectiveness of customer interactions.
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