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Achillion Pharmaceuticals (Nasdaq: ACHN) $2.38. Today announced the nomination of a lead clinical candidate in its third proprietary program against hepatitis C infection. The candidate, ACH-2684, demonstrates excellent potency in the low pico-molar range, as well as good pharmacokinetic and safety profiles in pre-clinical studies.
“The potency and virology profile of ACH-2684 demonstrates that it very effectively suppresses a broad range of natural variants of the hepatitis C virus, and may be effective in prevention and treatment of emerging resistant variants. This compound also retains potent activity against all genotypes. The very high potency of ACH-2684 was achieved by optimizing its interactions against NS3 protease. We have demonstrated in vitro that ACH-2684 can be used in combination with other HCV inhibitors, and that it is synergistic with NS5B nucleoside polymerase inhibitors,” said Milind S. Deshpande, Ph.D., Executive Vice President and Chief Scientific Officer of Achillion. “We have leveraged our expertise in HCV drug discovery and structure-based design to create a set of compounds, including ACH-2684, that are part of a discrete intellectual property estate and to which we currently retain all commercial rights."
What They Do: Achillion is an innovative pharmaceutical company dedicated to bringing important new treatments to patients with infectious disease. Achillion’s proven discovery and development teams have advanced multiple product candidates with novel mechanisms of action.
To read more about ACHN visit http://www.smallcapreview.com/achn.htm
Micrus Endovascular Corporation (Nasdaq: MEND) $16.62. Today announced that it will release financial results for the quarter ended December 31, 2009 before market open on Thursday, February 4, 2010. Micrus’ management will host an investment community conference call at 10:30 a.m. Eastern time (7:30 a.m. Pacific time) to discuss those results and answer questions.
Individuals interested in participating in the conference call may do so by dialing (888) 803-8296 for domestic callers, or (706) 679-0753 for international callers. Those interested in listening to the conference call live via the Internet may do so by visiting the Investor Relations section of the company’s Web site at www.micruscorp.com.
A telephone replay will be available for 48 hours following the conclusion of the call by dialing (800) 642-1687 for domestic callers, or (706) 645-9291 for international callers, and entering reservation code 50767198.
To read more about MEND visit http://www.smallcapreview.com/mend.htm
What They Do: Micrus develops, manufactures and markets implantable and disposable medical devices for use in the treatment of cerebral vascular diseases.
3D Systems Corporation (Nasdaq: TDSC) $10.79. Today announced that it has received a multi-year contract from a major helicopter manufacturer to produce various in-flight plastic components using its proprietary Selective Laser Sintering Production Systems and materials. This forward-thinking helicopter manufacturer recognizes the significant weight and cost savings gained by using the latest 3Dproparts™ Production Systems and materials to manufacture cost effective high performance aircraft components.
What They Do: 3D Systems is a leading provider of 3-D Printing, Rapid Prototyping and Manufacturing systems and parts solutions.
Imperial Sugar Company (NASDAQ: IPSU) $16.72. Today announced that it will release fiscal 2010 first quarter financial results before the market opens on Friday, February 5, 2010.
Company officials will conduct a conference call, starting at 11:00 a.m. Eastern, Friday, February 5, 2010. Imperial Sugar President and CEO John Sheptor and Senior Vice President and CFO Hal Mechler, will discuss the company’s operating results for its fiscal first quarter ended December 31, 2009, its current financial position and its business strategies.
To read more about IPSU visit http://www.smallcapreview.com/ipsu.htm
What They Do: Imperial Sugar Company is one of the largest processors and marketers of refined sugar in the United States to food manufacturers, retail grocers and foodservice distributors.
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