“Biology
and botany are having an unhealthy cannabinoid clash,” opened Bryan W. Brickner,
“and it’s about naming rights.”
In Homeostasis:
Publius’ Sleep Political Cannabinoid Science, new on the Bryan William Brickner
Blog, the focus is 2014 sleep research from the National Institutes of Health
(PubMed). The post highlights five cannabinoid system (CS) articles regarding:
de-homeostatic sleep disturbances, REM transitions, aging with THC, the
wake-inducing effects of CBD, and arousal sleep regulation.
The biology
botany cannabinoid clash is in the September PubMed article, Nabilone therapy
for cannabis withdrawal presenting as protracted nausea and vomiting; the
article argues for the use of Nabilone, a synthetic (pharmaceutical)
cannabinoid, for “Cannabis Withdrawal.” Brickner, part of Publius and publisher
of The Cannabis Papers: A citizen’s guide to cannabinoids (2011), considers the
conflict in its political nature: isn’t cannabis withdrawal really CS
deficiency?
“The withdrawal symptoms described,
irritability, nervousness, sleep disturbances and decreased appetite,”
explained Brickner, “are said to begin within 24 hours of abstinence after
chronic cannabis use; in terms of biology, the reported symptoms are from a
cannabinoid system in depletion and not from the absence of the plant
cannabinoids.”
“This one case,” noted Brickner, “is being
touted as evidence for using synthetic cannabinoids to ‘treat’ cannabis
withdrawal; yet it’s not cannabis withdrawal the pharmaceutical really treated
~ it treated the patient’s (now) lacking cannabinoids, which is known as clinical
endocannabinoid deficiency (CECD).”
“The
rest of the sleep CS science is calming (and not political),” closed Brickner,
“news on REM transitions, aging and wake-inducing CS effects, and arousal and
sleep regulation ~ you know, more of that homeostatic stuff.”
Homeostasis
next: Publius’ (Almost Scary) Political Cannabinoid Science, Thursday 30
October, followed on the 31st with a Halloween Dreamy Special.
Brickner has a 1997 political
science doctorate from Purdue University and is the author of several political
theory books, to include: The Promise Keepers (1999), Article the first (2006),
and The Book of the Is (2013). The Bryan William Brickner Blog is an
ongoing resource for the political science of constitutions and the biological
science of receptors.
The Cannabis Papers is available at online retailers and for
free by download.
