Topical retinoids, such as Differin ™, Epiduo™, Retin A Micro™ and Tazorac™ are a primary component of acne treatment because of their unique ability to open clogged pores. In cases of mild acne, these acne medications may be prescribed for use alone. In cases of moderate or severe acne, topical retinoids may be prescribed in combination with other acne treatments, such as benzoyl peroxide, antibiotics, or hormonal therapies. Some topical retinoids, such as Epiduo™ and Ziana™ are formulated in combination with other acne medications.
Jeffrey Ellis, M.D., a dermatologist in private practice at Belaray Dermatology stated that, "most patients with acne will benefit from a topical retinoid. It is one of the few medications we prescribe topically that helps to prevent new pimples from forming. Retinoids do not help patients overnight, but in the long run they can make acne much better.” Dr Jeffrey Ellis added that, “when starting a topical retinoid, it is important to use only a small amount. If used too aggressively, the medication can irritate the skin -- and discourage the patient. However, slow and steady use will result in reliable improvement of acne."
Marta Rendon, M.D., a dermatologist in private practice at the Dermatology and Aesthetic Center in Boca Raton Florida, commented that “retinoids play a crucial role in the management of acne. If a patient has comedonal acne alone, we will prescribe a topical retinoid as the main therapy and maybe add benzoyl peroxide. If a patient has inflammatory acne (with redness and pustules), we still start with a retinoid and add either a topical or oral antibiotic as needed.
Dr. Marta Rendon added that, "I tell my patients that they might get a bit dry at the beginning of treatment and sometimes mild redness. We call this the 'retinoid effect'. Eventually the skin normalizes and patients will be able to tolerate the retinoid very well. For those people with more sensitive skin, we have them use a non comedogenic moisturizer after applying the medication."
Topical retinoids are often prescribed for maintenance therapy to keep acne under control, prevent the development of acne scars and provide improved skin texture.
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