Celera Corporation (NASDAQ:CRA) rose 0.30% to $7.00 after today announced the publication of data reporting that elderly (over age 70) carriers of the KIF6 gene variant with prior vascular disease received significant benefit from pravastatin (Pravachol) therapy. Previous research has shown that a variant of the KIF6 gene, a member of the molecular motor protein kinesin family, is associated with up to a 55% increased risk of primary and recurrent coronary heart disease (CHD) events in the placebo arms of the clinical trials, and that this increased risk is virtually eliminated with statin therapy.
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Human Genome Sciences (NASDAQ:HGSI) surged 0.28% to $32.19 after today it announced interim results through Week 12 following the end of treatment in a Phase 2b clinical trial conducted by Novartis to evaluate the safety and efficacy of ZALBIN (albinterferon alfa-2b), an investigational agent, administered monthly in combination with ribavirin in 391 treatment-naive patients with genotypes 2 and 3 chronic hepatitis C virus.
Poniard Pharmaceuticals, Inc. (NASDAQ:PARD) fell 16.80% to $1.30 after said following a detailed analysis of primary and updated data from the Phase 3 SPEAR study of picoplatin in small cell lung cancer (SCLC) and an evaluation of the ongoing New Drug Application (NDA) process with the FDA, the Company has decided to suspend its efforts to obtain regulatory approval for picoplatin in SCLC at this time.
Genzyme Corporation (NASDAQ:GENZ) fell 4.40% to $56.51 after announced today that the FDA notified the company yesterday afternoon that, while the agency recognizes Genzyme’s efforts, it intends to take enforcement action to ensure that products manufactured at the plant are made in compliance with good manufacturing practice regulations.
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