NASDAQ Stock Movers on FDA Decision (CRXL, ENDP, VICL, BIIB)

Crucell N.V. (ADR) (NASDAQ:CRXL) rose 0.65% to $32.74 on heavy volume after Crucell N.V. (Nasdaq: CRXL) and the Aeras Global TB Vaccine Foundation announced today that they have commenced a Phase II of TB candidate, AERAS-402/Crucell Ad35, in infants.

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The first part of the trial will be conducted in Kenya to establish the optimal dosing level. once established, the selected does will be tested in the second part of the trial, expected to start in CY11, and take place in Kenya, Mozambique, South Africa and Uganda.

Endo Pharmaceuticals (NASDAQ:ENDP) rose 0.45% to $29.18 on heavy volume after it announces that their New Drug Application for a long-lasting oxymorphone, which is also designed for crush-resistance, has been granted priority review by the U.S. Food and Drug Administration.

Vical Incorporated (NASDAQ:VICL) plunged 38% to $2.40 after partner Sanofi-Aventis (NYSE: SNY) said late stage trials of NV1FGF failed to meet its goal of preventing limb amputation or deaths in patients with limb ischemia.

Vical Incorporated researches and develops biopharmaceutical products based on its deoxyribonucleic acid (DNA) delivery technologies for the prevention and treatment of serious or life-threatening diseases.

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Biogen Idec Inc. (NASDAQ:BIIB) fell 5.22% to $55.17 following FDA approval of Novartis' (NYSE: NVS) MS drug Gilenya.

The approval could be seen as competition for Biogen Idec's MS therapies AVONEX and TYSABRI. Biogen Idec also has three late-stage clinical candidates that target multiple pathways thought to be critical in treating MS.

Biogen Idec issued a statement on the Gilenya approval, which suggested to some the company is acting defensive.

The company stated, "MS impacts each person differently and, until we have a cure, there should be multiple treatments available to address the individual needs of patients."

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