Health2Go hired a Phd chemist with 18 years experience formulating and compounding topical transdermal creams to develop and test Twist 25
DHEA cream. There were 17 versions of the cream considered to develop the best possible cream mix. The cream is a highly specialized custom engineered nanoemulsion cream that delivers pharmaceutical grade bioidentical DHEA through the skin to the ideal place in the dermis for best metabolism. The small particle (about 200 micrograms) size makes Twist 25 cream unique allowing for optimal delivery of DHEA and a long shelf life (> 2 years). Health2Go did extensive Pilot study testing on the cream for safety and shelf life. In fact, safety studies were done with 50 human test subjects for 60 days; there were no irritations or adverse reactions to the cream. So you can have confidence in Twist 25 DHEA supplement cream knowing Health2Go, Inc. only sells the best possible DHEA cream. It's not the cheapest. It's the best. It works.
Recent medical research studies show
DHEA must be delivered to the body as a transdermal cream rather than as a pill supplement. There are 3 key reasons for this. 1) When taken as a pill, DHEA is destroyed by the "first-pass effect" of the liver. Basically, this means that because the molecule is too large and looks to your body like a foreign substance, the liver filters most of the effective DHEA out before it can do any good: and, what does end up getting into the bloodstream is DHEA-S (DHEA sulphate). DHEA-S is not the same as DHEA. DHEA-S has different benefits than DHEA…very different pro-hormones. DHEA-S is an entirely different thing than DHEA. Recent medical research shows that DHEA-S is not converted by the body into DHEA. DHEA is converted into DHEA-S, but not the other way around. So, basically, all the research studies that have been done in the past using oral DHEA supplements that showed little benefit to "DHEA"(Sulphate) were not testing the right thing with an effective method of administration. DHEA must be delivered to the body as a transdermal DHEA cream - Twist 25.