2008 U.S. Open Results: Serena, Venus Williams Set to Face-Off in Quarterfinals

Serena and Venus Williams will face-off in the quarterfinals of the 2008 U.S. Open on Wednesday.

The No. 7-seeded Venus defeated No. 9 Agnieszka Radwanska of Poland 6-1, 6-3, before No. 4 Serena dispatched wild-card entrant Severine Bremond of France 6-2, 6-2 at night.

Venus beat Serena for the title at Wimbledon in July in their seventh major title match. Wednesday will mark the first time they've squared off at consecutive Grand Slams since 2003.

Of the eight women left in the tournament, only two have won a Grand Slam title. Serena leads all active players with eight, and Venus is right behind with seven.

The Williams sisters won every U.S. Open women's singles championship from 1999 to 2002, meeting in the finals the last two years of that span.

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