In a previous article, entitled “What have scientists found to fight the leading cause of skin aging – mitochondrial decay?”, Glissandra Skincare discussed how Schisandrin B and (−)Schisandrin B have been proven to be successful in that regard, dramatically improving the appearance of aging skin. A study related to this was recently published in the Journal of Cosmetic Dermatology, the official publication of the International Academy of Cosmetic Dermatology. “Mitochondria: a new focus as an anti-aging target in skin care” confirms the important role of mitochondrial function in aging and advocates targeting mitochondria in the development of new products. Here, the use of Schisandrin B and (−)Schisandrin B is explored through the revolutionary new ingredient, Glissandrin™, which promises to change the way we approach skin care.
As discussed in previous articles, mitochondrial decay plays a fundamental role in the process of aging. Over time, cells lose the ability to function normally, falling victim to free radicals and the ensuing oxidative stress. The consequences of this appear as the visible signs of skin aging, including wrinkles, fine lines, age spots, loss of suppleness, and a marked deterioration in skin tone.
Glissandrin™: Glissandrin™ is a suite of natural compounds isolated from the Schisandra berry. Consisting mainly of Schisandrin B and (−)Schisandrin B, Glissandrin™ also comprises (±)γ-Schisandrin, Schisandrin A, and Schisandrin C. Extensive research on Glissandrin™ has confirmed its anti-aging properties on skin cells, most notably on its ability to target the fundamental cause of aging: mitochondrial decay.
Research Findings
* Mitochondrial decay in skin cells can be reversed by topical application of Glissandrin™: A 3-day application of Glissandrin™ cream (2% and 5%) to skin cells caused a dose-dependent increase in reduced glutathione (GSH) and α-tocopherol (α-Toc) levels in skin mitochondria. Glissandrin™ cream is able to enhance the antioxidant capacity of mitochondria and to reverse mitochondrial decay in aging skin cells.
* Mitochondrial functional capabilities in skin cells can be enhanced by topical application of Glissandrin™: Glissandrin™ also dose-dependently increased mitochondrial ATP (cellular energy) production in human skin cells, indicative of enhancement in mitochondrial functional ability.
* In-vivo and in-vitro studies have confirmed other properties of Glissandrin™ that are beneficial to the skin: emolliating proliferative skin conditions; enhancing the natural antioxidative capabilities in skin cells; increasing the expression of cellular heat shock proteins, thereby alerting the skin to adverse external environmental factors; suppressing inflammation; inhibiting the production of collagenase, an enzyme that destroys collagen; protecting skin cells from solar radiation – particularly UV – and repairing skin cells with UV damage; reducing the destruction of elastin, a protein in the skin matrix responsible for skin elasticity; inhibiting ATR protein kinase activity (cancer prevention)
Glissandrin™ has been clinically tested to be safe for even the most sensitive skin, especially for users who experience adverse reactions to most skincare products. The desired level of biological availability and the purity of chemical compositions of Glissandrin™ are standardized through a proprietary process developed specifically for its manufacturing. Furthermore, the concentrations of the constituent compounds have been formulated for easy absorption, optimal efficacy, and a luxurious feel when applied to the skin.
The International Academy of Cosmetic Dermatology has spoken, and its message is clear: targeting mitochondrial decay is now the goal of the anti-aging industry. Without understanding and addressing mitochondrial decay, the leading cause of skin aging, most skincare products are ill-equipped to provide the real, sustainable results they promise. Fortunately, Glissandrin™ is available today as the ultimate anti-aging skincare solution.
About Glissandra™ Skincare Inc.:
Glissandra™ Skincare Inc. is a network marketing company (also known as multi-level marketing, MLM, or direct sales) dedicated to providing effective anti-aging skincare through its holistic approach to skin health. Glissandra’s comprehensive skincare system is the result of over 20 years of research and development at the Hong Kong University of Science and Technology, led by Dr. Robert Ko. Over 100 research papers have been published on its key proprietary ingredient, Glissandrin™, a suite of natural compounds extracted from the Schisandra berry. In-vivo and in-vitro studies have proven the ability of Glissandrin™ to address mitochondrial decay, the leading cause of aging, and to enhance the cell’s natural ability to fight oxidative damage.
Contact:
Glissandra Skincare
Glissandra™ Skincare Inc.
305-5811 Cooney Road
Richmond, BC
Canada V6X3M1
1-877-313-7242
