Rochester, NY 7/15/2009 3:34:34 AM
AVII - AVI BioPharma, Inc. Presents at American Society of Virology Annual Meeting
AVI Biopharma, Inc.
AVI Biopharma, Inc., AVII
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AVI BioPharma, Inc., a developer of RNA-based drugs, today announced that Dr. Fred Schnell of AVI presented at the American Society of Virology Annual Meeting which took place July 11-15 in Vancouver, B.C. The title of the presentation was "Pan-Arenavirus Antisense Therapeutic Based On PMOplus(TM) Chemistry." In addition to Dr. Schnell, Drs. Bestwick, Iversen and Mourich, all of AVI, coauthored the presentation. Schnell presented results of preclinical findings using an antiviral oligomer compound that incorporates AVI's proprietary backbone chemistry (PMOplus(TM)). The work shows that a single oligomer blocks a terminal sequence common to the eight distinct RNAs expressed by viruses from the family of hemorrhagic fever arenaviruses. Because this sequence is highly conserved among arenaviruses, a single agent might serve as a pan-arenavirus drug. Arenaviruses include Lassa fever, lymphocytic choriomeningitis, Junin and Machupo viruses, all members of the Class A bioterrorism pathogen list.
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