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TorreyPines Therapeutics Inc. (NASDAQ:
RPTPD) climbed 22% to $4.09 on 260K shares within few minutes of trade after it announced positive findings from the completed treatment phase of its open-label Phase 2a clinical trial of delayed-release cysteamine bitartrate ("DR Cysteamine") in adolescent patients with non-alcoholic steatohepatitis ("NASH"), a progressive form of liver disease believed to affect 2% to 5% of the U.S. population. At the completion of the initial six-month treatment phase, the study achieved the primary endpoint: mean blood levels of alanine aminotransferase ("ALT"), a common biomarker for NASH, were reduced by over 50%. Additionally, over half of the study participants had achieved normalized ALT levels by the end of the treatment phase.
TorreyPines Therapeutics, Inc. (TorreyPines) is a biopharmaceutical company committed to providing patients with alternatives to existing therapies through the research, development and commercialization of small molecule compounds. The Company seeks to develop product candidates each capable of treating a number of acute and chronic diseases and disorders, such as migraine, acute and chronic pain, and xerostomia.
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