Scottsdale 12/18/2010 1:33:06 AM
Manhattan Pharmaceuticals (MHAN.OB) Announces Positive Results of Essential Tremors Treatment
QualityStocks would like to highlight Manhattan Pharmaceuticals (OTCBB: MHAN), a specialty healthcare product company focused on the development and commercialization of innovative treatments for underserved patient populations. The company is currently focused on two lead programs: AST-726, a nasally delivered vitamin B12 remediation treatment, and Hedrin(R), a novel, non-insecticide treatment for pediculosis (head lice), which is being developed through a joint venture with Nordic Biotech.
In the company’s news yesterday,
Manhattan Pharmaceuticals posted its results from a phase I/II study of AST-915 to treat essential tremors, a movement disorder that causes involuntary shaking of the hands, arms, head, voice, and upper body.
The company reported that data from the single does study showed AST-915 as safe and well-tolerated with an obvious effect on the tremors. While there was no statistically significant effect on tremor power after 80 minutes of administration of the treatment, statistically significant reductions were evident at later time, up to 300 minutes after administration.
“This early positive data in subjects with essential tremor clearly demonstrates human proof of concept and indicates a need to explore the effect of higher doses and longer term administration of AST-915,” Malcolm Morville, PhD, director of Manhattan Pharmaceuticals stated in the press release.
The study was conducted at The National Institute of Neurological Disorders and Stroke (NINDS) at the National Institutes of Health (NIH) in terms of a CRADA agreement between the NIH and Ariston Pharmaceuticals Inc., a wholly owned subsidiary of Manhattan Pharmaceuticals.
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