Rochester,NY 7/7/2009 3:06:45 AM
News / Finance

Late Afternoon Report - SNY - Sanofi-Aventis study shows Lantus safety on eyes - Sourced WhisperFromWallStreet.com

Sanofi-Aventis

Late Afternoon Report - SNY - Sanofi-Aventis study shows Lantus safety on eyes - Sourced WhisperFromWallStreet.com

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Sanofi-Aventis,SNY


After Hours: 30.28 Up 0.58 (1.95%)  3:59pm ET

Drug developer Sanofi-Aventis said Monday its long-acting insulin Lantus was as safe in a five-year study as older types of insulin, specifically in cases of poor eyesight and blindness.
The five-year study showed that Lantus did not have a higher number of diabetic retinopathy cases, compared with older types of insulin called neural protamine hagedorn. Diabetic retinopathy is a complication from diabetes that can lead to blindness. The study involved 1,024 patients.

Paris-based Sanofi-Aventis said the results are being published online in the journal Diabetolgia. The statement comes on the heels of health concerns over Lantus and its possible link to an increased risk of cancer. Last week, the Food and Drug Administration said it is reviewing data on Lantus.

That move followed the European Association for the Study of Diabetes' concerns over a review of an insurance database. That database of 127,000 patients in four European countries found that out of every 100 patients using Lantus for about 1 1/2 years, one additional person developed cancer.

The association called the results inconclusive and urged further study. The American Diabetes Association has urged patients to speak with their physician before making any decision to stop treatment with Lantus.

About

Sanofi-Aventis, a pharmaceutical company, contributes to enhancing life by providing an offering of medicines, vaccines, and integrated healthcare solutions adapted to local needs and means primarily in Europe and the United States. The company has products in the areas of thrombosis, cardiovascular, metabolic diseases, oncology, central nervous system, internal medicine, and vaccines. Its primary medicines include Lovenox/Clexane, Plavix/Iscover, Aprovel/Avapro/Karvea, Tritace/Triatec/Delix/Altace, Lantus, Amaryl/Amarel/Solosa, Acomplia, Taxotere, Eloxatine, Stilnox/Ambien/Myslee, Copaxone, Depakine, Allegra/Telfast, Nasacort, Xatral/Uroxatral, and Actonel/Optinate/Acrel. The company?s vaccines principally include pediatric combination and poliomyelitis vaccines, influenza vaccines, meningitis/pneumonia vaccines, adult and adolescent booster vaccines, and travel and endemic vaccines. It has collaboration agreements principally with Novozymes, Dyax Corp., Oxford BioMedica, Regeneron, IDM, Zealand Pharma, UCB, and Crucell N.V., as well as partners, including Immunogen, Coley, Wayne State University, Innogenetics, and Inserm. The company also has an agreement with Drugs For Neglected Diseases Initiative (dndi) for the development, manufacturing, and distribution of fexinidazole, a drug for the treatment of human African trypanosomiasis. Sanofi-Aventis was founded in 1970 and is headquartered in Paris, France.

Last Trade:    30.27
Day's Range:    29.83 - 30.30
52wk Range:    23.95 - 37.11
Volume:          1,741,672
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